Publications
Research & Citation
MultiEndpointTox is developed in the open. Organized by real publication status — no placeholders standing in for work that doesn't exist yet.
Published
No publication record has been verified yet — the manuscript below is accepted, not yet published (no volume, issue, or DOI has been assigned).
Accepted for Publication
MultiEndpointTox: A Chemoinformatics Platform for Multidimensional Drug Toxicity Profiling Using Interpretable Machine Learning, Multi-Task Learning, and Integrated Risk Scoring
Sharhabil Amgad Eltahir; Mukhtar Ibrahim Yousef · Pharmaceuticals (MDPI) · Accepted 6 August 2026
A chemoinformatics platform for multidimensional drug toxicity profiling — full methodology, validation, and case studies. No DOI, volume, or issue has been assigned yet; the certificate below documents the acceptance itself.
Conference Presentations
Metabolism-Aware and Pharmacogenetics-Informed Toxicity Prediction: A Multi-Endpoint Machine Learning Framework With Systematic Platform Benchmarking
Sharhabil Amgad Eltahir Mohamedali · SETAC North America 47th Annual Meeting · Montreal, Quebec · Wednesday, 4 November 2026
A platform presentation (id#20648) on metabolism-aware, pharmacogenetics-informed multi-endpoint toxicity prediction with systematic platform benchmarking against existing tools.
Preprints
No preprint was posted — the manuscript proceeded directly from submission to peer-reviewed acceptance.
In Preparation
TODO: Documentation not yet available.
Software Release (citable now)
MultiEndpointTox: Multi-Endpoint Toxicity Prediction Platform for Drug Safety Assessment with OpenTox 2.0-Aligned Workflows
Sharhabil Amgad Eltahir Mohamedali · Zenodo · v1.2 · 2026-03-10
MultiEndpointTox is a machine-learning REST API for predicting seven drug toxicity endpoints from molecular SMILES strings: hERG cardiotoxicity (regression), drug-induced liver injury (DILI), nephrotoxicity, Ames mutagenicity, skin sensitization, cytotoxicity, and reproductive/developmental toxicity (all classification). Predictions include SHAP feature attribution, structural alert detection, applicability domain assessment, and integrated risk scoring. Implements OpenTox 2.0 compliance principles for FAIR, interoperable, and auditable computational toxicology.
Related reading
Abdelwahab, S. & Hardy, B. (2026). OpenTox 2.0: A Framework for Regulatory-Grade Toxicity Prediction. Journal of Cheminformatics — the compliance framework MultiEndpointTox implements. Not a MultiEndpointTox publication.